A skin is probably the first piece of the puzzle that will be a new computer. The thing you will learn from understanding about computer cases, and for that matter all the other posts in this series, you will probably need some idea of the other parts of a computer that you want. The kind of skin, in part, is dependent on things like what motherboards you may want, or how many hard drives or solid state drives you will use. So, before going out and buying a skin, be sure you have an idea about other parts of the computer you may be looking for.
The first, and perhaps most, important aspect of a case is how big you want it. There are, for example, from smallest to largest, mini-Towers, mid-towers, and full towers. They are associated, in order, with mini-ITX and microATX, ATX, and E-ATX. They are backwards compatible. In other words, the full tower can hold the E-ATX and a microATX, but a mini-tower can in no way hold a E-ATX. Most people suggest getting a mid-tower. That being said, the larger the case, more than likely, the more expensive it will be. So, most people will get a mid-tower instead of a full tower due to price and practicality. A mid-tower will probably have everything you will need and have the space for the other parts of the computer you will get later on.
Then there is the front. The front has a panel of buttons and uses. Though sometimes, the 'front panel' is located on the top. This panel includes the power and reset buttons, like usual. However, it also tends to have things like USBs and a headphone jack. As time has gone on, USBs have evolved. USBs can be 2.0 which is what most people are familiar with. However, there is also 3.0, 3.1, and 3.2. They are interchangeable in use, but not in speed. In other words, if you hook a 3.2 gen USB into a 2.0 USB port, it will run at a 2.0 USB speed. On some front panels there is a fan control for the fans inside the case. As well as the front panel, there may be slots for optical drives. Optical drives are like cd or Blu-ray players. They are the 5.25" drive bays. However, these have slowly been phasing out of use. There are USB alternatives that are available.
This leads to the back of the case. The back of the skin will have a few holes and places for holes. The largest of these holes is for the I/O shield. This is usually in conjunction with the motherboard. This is because most motherboard's back panel will be different from others. This is where the back USBs and video plugs will be located. The video plugs can range from VGA to HDMI to the new Display Ports. Below this is where expansion slots are located. These may vary from network cards to video (or graphics) cards. Finally on the back is where you will see the outside of the PSU (power supply unit). You will need to screw the PSU into the skin from the outside. Some PSUs will be on top, but my experience has always had them on the bottom.
Now let’s venture to the inside of the case. If at all possible, look for the phrase tool-free because the less tools needed will make the building of a computer far less cumbersome. Beyond that, there are a few things to look out for and few questions you may need to ask yourself. For one, this is where size matters. If you are trying to get a smaller case, then this will affect the motherboard tray. As has been discussed a larger motherboard will not fit in a smaller skin. Though nowadays it has become a common practice for mid-towers to be able to hold E-ATX boards. Though, there will be less room, obviously, to work with than using a normal ATX. As you are building your computer, you will learn how important room can be.
The first question to ask yourself is how am I going to store my data. The old fashion way to hold onto data is through an HDD or hard drive. This is where the 3.5-inch bay comes into effect. They are the cheaper option, and gives you more storage space for the buck. However, they are the slower alternative and has a greater possibility of going bad. You take a greater risk with HDDs than the alternative SSD. The 3.5-inch bays are becoming less and less a part of skins though many still have them. They can come in the form of just a bay in the computer to having driven sleds that slide in and out of the different bays. Most motherboards and PSUs give the availability to have multiple drives connecting your computer.